Joint Discrete and SE(3) Diffusion for Protein Interface Design

cs.AI

Submitted: 2026-10-10

Updated: 2026-10-10

License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/

Sources

• An All-Atom Generative Model for Designing Protein Complexes
• Score-Based Generative Modeling through Stochastic Differential Equations
• PPDiff: Diffusing in Hybrid Sequence-Structure Space for Protein-Protein Complex Design
• Diffusion probabilistic modeling of protein backbones in 3D for the motif-scaffolding problem
• Diffusion Language Models Are Versatile Protein Learners
• SE(3) diffusion model with application to protein backbone generation
• De novo design of high-affinity protein binders with AlphaProteo

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