CODesign: Consistency from Data to Trajectory in All-Atom Protein Binder Co-Design

arXiv:2610.01773 · cs.CE, cs.AI · Submitted 2026-10-01 · Read on arXiv

cs.CE, cs.AI

Submitted: 2026-10-01

Updated: 2026-10-01

License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/

Terminology

• Consistency — 1× in this paper · explained in 3 episodes

Sources

• Generative Flows on Discrete State-Spaces: Enabling Multimodal Flows with Applications to Protein Co-Design
• A-CODE: Fully Atomic Protein Co-Design with Unified Multimodal Diffusion
• General Multimodal Protein Design Enables DNA-Encoding of Chemistry
• Consistent Synthetic Sequences Unlock Structural Diversity in Fully Atomistic De Novo Protein Design
• De novo design of high-affinity protein binders with AlphaProteo

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