Geometry-anchored PET-aware multimodal pseudo-CT synthesis for whole-body attenuation correction: the BIC-MAC Challenge

arXiv:2609.27848 · cs.CV · Submitted 2026-08-19 · Read on arXiv

cs.CV

Submitted: 2026-08-19

Updated: 2026-08-19

Comments: Challenge paper for the Big Cross-Modal Attenuation Correction (BIC-MAC) Challenge at MICCAI 2026

Project page: https://bic-mac-challenge.github.io

License: http://creativecommons.org/licenses/by-nc-nd/4.0/

The gist: The BIC-MAC challenge targets whole-body pseudo-CT synthesis from NAC-PET, Dixon MRI, and a 2D topogram for CT-less PET attenuation correction.

Terminology

Abstract

The BIC-MAC challenge targets whole-body pseudo-CT synthesis from NAC-PET, Dixon MRI, and a 2D topogram for CT-less PET attenuation correction. We propose GeoPACT, a geometry-anchored multimodal framework that uses NAC-PET as the spatial reference and incorporates topogram and MRI features through gated residual fusion. Absolute coordinates and whole-body conditioning support anatomically consistent patch-based prediction. Training combines attenuation-map supervision with a differentiable PET-response surrogate to reduce errors relevant to downstream PET reconstruction. Full-resolution pseudo-CT volumes are generated using sliding-window inference without requiring CT or PET labels at test time.

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