RNAGenScape: Property-Guided, Optimized Generation of mRNA Sequences with Manifold Langevin Dynamics

arXiv:2510.24736 · q-bio.QM, cs.LG, q-bio.BM · Submitted 2025-10-14 · Read on arXiv

q-bio.QM, cs.LG, q-bio.BM

Submitted: 2025-10-14

Updated: 2026-10-10

Terminology

• Langevin Dynamics — 3× in this paper · explained in 2 episodes
• Local Optimization — 1× in this paper · explained in 2 episodes

Sources

• Back to Basics: Let Denoising Generative Models Denoise
• Manifold Preserving Guided Diffusion
• Flow Matching for Generative Modeling
• Variational auto-encoding of protein sequences

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