VEDA: Generation of 3D Molecules via Variance-Exploding Diffusion with Annealing
VEDA introduces a unified SE(3)-equivariant framework combining variance-exploding diffusion with annealing to generate accurate 3D molecular structures efficiently. It solves the trade-off between fast sampling and structural accuracy by using a noise schedule analogous to simulated annealing, leading to remarkably stable conformations with low relaxation energy.