Extraction of geometric and transport parameters from the time constant of exocytosis transients measured by nanoscale electrodes
The study extracts geometric and transport parameters from exocytosis transient decay signals measured by nanoscale electrodes. An analytical model was developed using equation 7 to predict the time constant (τ) of these signals based on pore width, vesicle size, and diffusion coefficients. This model is validated against detailed simulations and experimental data, providing a closed-form expression for accurate parameter estimation.