Registration-Grounded Spectral Fusion for Unregistered WLI/NBI Endoscopic Lesion Segmentation

The framework addresses misaligned White-light imaging (WLI) and Narrow-band imaging (NBI) by first establishing reliable topological correspondence using topology-regularized registration. It then fuses these modalities in a complex spectral domain, selectively combining WLI's appearance cues with NBI's structural cues based on local reliability maps. This approach ensures accurate segmentation even when images are not perfectly registered.

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