Establishing the Minimal Clinically Important Difference (MCID) for Smartphone-Derived Gait Measures in Multiple Sclerosis
The study established Minimal Clinically Important Differences (MCIDs) for smartphone-derived gait measures in progressive Multiple Sclerosis (MS). Researchers used data from a phase 3b trial to find specific, meaningful changes in metrics like step velocity and total distance walked. These thresholds provide a framework for interpreting remote monitoring data and evaluating disease progression.