How deterministic trajectories and their fluctuations underlie allele-frequency statistics in the strong-selection regime

The study develops an approximation method to calculate allele-frequency statistics under strong selection ($R eq 1$). It addresses errors caused by ignoring trajectories leading to allele loss by conditioning the statistic on whether fixation or loss occurs. A small noise expansion is used to capture transient behaviors, providing a computationally efficient tool for analyzing time-dependent allele frequency statistics in experimental evolution.

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